- Networks
- Planning for student-led sessions
Today's Topics
But first…
- Short answers means short sentences.
- Be complete. Show me that you know what you're talking about.
Resting potential ~ -70 mV
| Ion | [inside] | [outside] | Conc Gradient | Equil potential | Driving force | Electrostatic gradient |
|---|---|---|---|---|---|---|
| \(K^+\) | ~150 mM | ~4 mM | outward | ~-90 mV | +20 mV | outward |
| \(Na^+\) | ~10 mM | ~140 mM | inward | ~+55 mV | -125 mV | inward |
Components
- Nodes
- Edges
Measures of
- Size
- Density
- Degree (# of edges)
- Centrality
- Motifs
- Path length
Types
- Directed vs. undirected
- Weighted vs. binarized
- Structural (wiring), functional (activity covariance), effective (causal)
Temporal (speed) vs. spatial (wiring) constraints
Some networks in the "resting" brain
Prepping for student presentations
| Group Theme | Members | Presentation Day? |
|---|---|---|
| Measuring brain & behavior | Kelley, Anna, Alison, Lauren, Rhea | |
| Neurodegeneration & disorder | Kaitlin, Sam, Daryl, Emily | |
| Development, aging, & plasticity | Liz, Michael, Lia, Chloe | |
| Cognition & emotion | Austen, Brandon, Shane, Emily |
Not assigned: Natalia, Nate
Scope of group presentations
- Provide 2-3 background readings in advance
- 25 min (max) presentation + 10 min discussion
- Focused themes + integrative section
- What have we learned/what do we know?
- What don't we know?
- Why are these answers important to know?
- How does topic X relate to/inform another theme?
- Submit slides
- Statement about who did what
References
Raichle, M. E. (2015). The brain’s default mode network. Annual Review of Neuroscience, 38, 433–447. https://doi.org/10.1146/annurev-neuro-071013-014030
Rubinov, M., & Sporns, O. (2010). Complex network measures of brain connectivity: Uses and interpretations. NeuroImage, 52(3), 1059–1069. https://doi.org/10.1016/j.neuroimage.2009.10.003
Sejnowski, T. J., Churchland, P. S., & Movshon, J. A. (2014). Putting big data to good use in neuroscience. Nat. Neurosci., 17(11), 1440–1441. https://doi.org/10.1038/nn.3839
Stiso, J., & Bassett, D. S. (2018). Spatial embedding imposes constraints on neuronal network architectures. Trends in Cognitive Sciences, 22(12), 1127–1142. https://doi.org/10.1016/j.tics.2018.09.007
Swanson, L. W., & Lichtman, J. W. (2016). From cajal to connectome and beyond. Annual Review of Neuroscience, 39, 197–216. https://doi.org/10.1146/annurev-neuro-071714-033954