Cellular neuroscience I

PSY 511.003

2025-01-30

Prelude

http://www.gregadunn.com/

National Geographic (2014)

In the news…

Eckert et al. (2024)

Our results suggest that individual cells may exhibit habituation behavior as rich as that which has been codified in multi-cellular animals with central nervous systems and that the relative simplicity of the biomolecular level may enhance our understanding of the mechanisms of learning.

Eckert et al. (2024)

I contain multitudes…

Whitman (2019)

Announcements

• Exercise 01
  • Scores
  • Themes
  • Implications
• Exercise 03 distributed.
  • due in two weeks on Wednesday, February 7

Last time…

• Neuroanatomy

Where is the cerebellum found?

In what lobe would one find primary somatosensory cortex?

What structure in the diencephalon controls the endocrine system and both branches of the autonomic nervous sytem?

Today’s topics

• Cellular neuroscience
  • Neurons
  • Glia
• Resting potential

Break

Work on Exercise 03

• Visit Exercise 03

Main points

• Cells of nervous system specialized
• Convey, process, store information
• Nervous systems enable complex external (behavior) and internal states
• Complex behavior/internal states not reducible to, but inseparable from nervous system states
• Electrical + chemical information flows

Next time…

• The action potential

Resources

References

Eckert, L., Vidal-Saez, M. S., Zhao, Z., Garcia-Ojalvo, J., Martinez-Corral, R., & Gunawardena, J. (2024). Biochemically plausible models of habituation for single-cell learning. Current Biology: CB, 34, 5646–5658.e3. https://doi.org/10.1016/j.cub.2024.10.041

National Geographic. (2014, January). Beautiful 3-D brain scans show every synapse | national geographic. YouTube. Retrieved from https://www.youtube.com/watch?v=nvXuq9jRWKE

Whitman, W. (2019, February 13). Song of myself, 51. Retrieved January 30, 2025, from https://poets.org/poem/song-myself-51