Schedule
Week 1
Thursday, January 11
Topics
- Structure of the course
- Levels of analysis
- Causality in brain and behavior
- Does neuroscience need behavior? If so, what does psychology need?
Readings
- (Siddiqi, Kording, Parvizi, & Fox, 2022).
- (Krakauer, Ghazanfar, Gomez-Marin, MacIver, & Poeppel, 2017).
- Optional: (Parada & Rossi, 2018)chrome.
- Optional: (Churchland & Sejnowski, 1988).
- Optional: (Favela, 2020).
Materials
- Slides
- Exercise 01 assigned
Week 2
Wednesday, January 17
- Exercise 01 write-up due.
Thursday, January 18
Topics
- Neuroanatomy lab
Readings
Materials
- Slides
- Allen Brain Atlas.
- Exercise 02 distributed
Week 3
Wednesday, January 24
- Exercise 02 write-up due.
Thursday, January 25
Topics
- Cellular neuroscience I
- Anatomy
- Physiology
- Resting potential
Readings
- Cellular neuroscience notes
- Optional: (Zeng & Sanes, 2017).
- Optional: (Oliveira, Sardinha, Guerra-Gomes, Araque, & Sousa, 2015).
- Optional: (Distéfano-Gagné, Bitarafan, Lacroix, & Gosselin, 2023).
Materials
- Slides
- Exercise 03 distributed.
Week 4
Thursday, February 1
Topics
- Cellular neuroscience II
- Action potential
- Synaptic transmission
- Exercise 04 assigned
Readings
Materials
Week 5
Wednesday, February 7
- Exercise 03 write-up due.
Thursday, February 8
Topics
- Neurochemistry
- Neurotransmitters
- Hormones
- Neurocomputing
Readings
- Neurochemistry notes
- Optional: (Sarkar et al., 2016).
Materials
- Slides
- Exercise 05 distributed
Week 6
Wednesday, February 14
- Exercise 04 write-up due.
Thursday, February 15
Topics
- Methods in neuroscience
Readings
- Methods notes
- Watch: (MITCBMM, 2019)
- Review: (“Cognitive psychology and cognitive Neuroscience/Behavioural and neuroscience methods,” n.d.).
- Recommended: (Cohen, 2017).
- Recommended: (Hillman, 2014).
- Optional: (Koch et al., 2022).
Materials
- Notes
- Exercise 06 distributed.
Week 7
Wednesday, February 21
- Exercise 05 write-up due.
Thursday, February 22
Topics
- Evolution of the nervous system
Readings
- evolution resources
- (Charvet & Finlay, 2012)
- (Hofman, 2014)
- Optional: (Castrillon et al., 2023).
Materials
- Notes
- Exercise 07 distributed
Week 8
Wednesday, February 28
- Exercise 06 write-up due.
Thursday, February 29
Topics
- Development of the nervous system
Readings
- Methods notes
- (Cao, Huang, & He, 2017).
- (Blumberg & Adolph, 2023).
- Optional: (Larsen, Sydnor, Keller, Yeo, & Satterthwaite, 2023).
- Optional: (Rakic, 2009).
Materials
- Notes
- Exercise 08 distributed
Due
Spring Break
Monday, March 4 - Friday March 8
NO CLASS
Week 9
Wednesday, March 13
- Exercise 07 write-up due.
- Exercise 08 write-up due.
Thursday, March 14
Topics
- Perception
Readings
Materials
Week 10
Thursday, March 21
Topics
- Action
Readings
Materials
Week 11
Thursday, March 28
Topics
- Language & cognition
Readings
- Watch: (MITCBMM, 2018).
- (Hagoort & Indefrey, 2014).
- (Anderson, Pyke, & Fincham, 2016).
Materials
Week 12
Thursday, April 4
Topics
- Learning & memory
Readings
Materials
Week 13
Thursday, April 11
Topics
- Disorder & disease I
Readings
Materials
Week 14
Thursday, April 18
Topics
- Disorder & disease II
Readings
Materials
Week 15
Thursday, April 25
Topics
- Fear, stress, pleasure, & reward
Readings
Materials
Week 16
Thursday, May 2
- Final papers due by 5:00 pm
References
Anderson, J. R., Pyke, A. A., & Fincham, J. M. (2016). Hidden stages of cognition revealed in patterns of brain activation. Psychological Science, 27(9), 1215–1226. https://doi.org/10.1177/0956797616654912
Blumberg, M. S., & Adolph, K. E. (2023). Protracted development of motor cortex constrains rich interpretations of infant cognition. Trends in Cognitive Sciences, 27(3), 233–245. https://doi.org/10.1016/j.tics.2022.12.014
Campbell, R. R., & Lobo, M. K. (2023). Pallidal circuits drive addiction behavior. Trends in Neurosciences, 46(12), 1042–1053. https://doi.org/10.1016/j.tins.2023.10.001
Cao, M., Huang, H., & He, Y. (2017). Developmental connectomics from infancy through early childhood. Trends in Neuroscience, 40(8), 494–506. https://doi.org/10.1016/j.tins.2017.06.003
Castrillon, G., Epp, S., Bose, A., Fraticelli, L., Hechler, A., Belenya, R., … Riedl, V. (2023). An energy costly architecture of neuromodulators for human brain evolution and cognition. Science Advances, 9(50), eadi7632. https://doi.org/10.1126/sciadv.adi7632
Charvet, C. J., & Finlay, B. L. (2012). Chapter 4 - embracing covariation in brain evolution: Large brains, extended development, and flexible primate social systems. In M. A. Hofman & D. Falk (Eds.), Progress in brain research (Vol. 195, pp. 71–87). Elsevier. https://doi.org/10.1016/B978-0-444-53860-4.00004-0
Churchland, P. S., & Sejnowski, T. J. (1988). Perspectives on cognitive neuroscience. Science, 242(4879), 741–745. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/3055294
Cohen, M. X. (2017). Where does EEG come from and what does it mean? Trends in Neurosciences, 40(4), 208–218. https://doi.org/10.1016/j.tins.2017.02.004
Distéfano-Gagné, F., Bitarafan, S., Lacroix, S., & Gosselin, D. (2023). Roles and regulation of microglia activity in multiple sclerosis: Insights from animal models. Nature Reviews. Neuroscience, 24(7), 397–415. https://doi.org/10.1038/s41583-023-00709-6
Favela, L. H. (2020). Cognitive science as complexity science. Wiley Interdisciplinary Reviews. Cognitive Science, 11(4), e1525. https://doi.org/10.1002/wcs.1525
Hagoort, P., & Indefrey, P. (2014). The neurobiology of language beyond single words. Annu. Rev. Neurosci., 37, 347–362. https://doi.org/10.1146/annurev-neuro-071013-013847
Hillman, E. M. C. (2014). Coupling mechanism and significance of the BOLD signal: A status report. Annual Review of Neuroscience, 37, 161–181. https://doi.org/10.1146/annurev-neuro-071013-014111
Hofman, M. A. (2014). Evolution of the human brain: When bigger is better. Frontiers in Neuroanatomy, 8. https://doi.org/10.3389/fnana.2014.00015
Howes, O. D., Bukala, B. R., & Beck, K. (2023). Schizophrenia: From neurochemistry to circuits, symptoms and treatments. Nature Reviews. Neurology. https://doi.org/10.1038/s41582-023-00904-0
Hu, H. (2016). Reward and aversion. Annual Review of Neuroscience, 39, 297–324. https://doi.org/10.1146/annurev-neuro-070815-014106
Hunt, M. J., Kopell, N. J., Traub, R. D., & Whittington, M. A. (2017). Aberrant network activity in schizophrenia. Trends in Neurosciences, 40(6), 371–382. https://doi.org/10.1016/j.tins.2017.04.003
Koch, C., Svoboda, K., Bernard, A., Basso, M. A., Churchland, A. K., Fairhall, A. L., … Zador, A. M. (2022). Next-generation brain observatories. Neuron, 110(22), 3661–3666. https://doi.org/10.1016/j.neuron.2022.09.033
Krakauer, J. W., Ghazanfar, A. A., Gomez-Marin, A., MacIver, M. A., & Poeppel, D. (2017). Neuroscience needs behavior: Correcting a reductionist bias. Neuron, 93(3), 480–490. https://doi.org/10.1016/j.neuron.2016.12.041
Larsen, B., Sydnor, V. J., Keller, A. S., Yeo, B. T. T., & Satterthwaite, T. D. (2023). A critical period plasticity framework for the sensorimotor-association axis of cortical neurodevelopment. Trends in Neurosciences, 46(10), 847–862. https://doi.org/10.1016/j.tins.2023.07.007
MITCBMM. (2018, August). Tutorial: Cognitive neuroscience. Youtube. Retrieved from https://www.youtube.com/watch?v=yTbHUwz4MN8
MITCBMM. (2019, September). Neuroscience methods tutorial. Youtube. Retrieved from https://www.youtube.com/watch?v=iHthMSN65bA
Moncrieff, J., Cooper, R. E., Stockmann, T., Amendola, S., Hengartner, M. P., & Horowitz, M. A. (2022). The serotonin theory of depression: A systematic umbrella review of the evidence. Molecular Psychiatry. https://doi.org/10.1038/s41380-022-01661-0
Murray, M. M., Lewkowicz, D. J., Amedi, A., & Wallace, M. T. (2016). Multisensory processes: A balancing act across the lifespan. Trends in Neurosciences, 39(8), 567–579. https://doi.org/10.1016/j.tins.2016.05.003
Musazzi, L., Tornese, P., Sala, N., & Popoli, M. (2017). Acute or chronic? A stressful question. Trends in Neurosciences. https://doi.org/10.1016/j.tins.2017.07.002
Namkung, H., Kim, S.-H., & Sawa, A. (2017). The insula: An underestimated brain area in clinical neuroscience, psychiatry, and neurology. Trends in Neurosciences, 40(4), 200–207. https://doi.org/10.1016/j.tins.2017.02.002
Nielsen, J. B. (2016). Human spinal motor control. Annual Review of Neuroscience, 39, 81–101. https://doi.org/10.1146/annurev-neuro-070815-013913
Oliveira, J. F., Sardinha, V. M., Guerra-Gomes, S., Araque, A., & Sousa, N. (2015). Do stars govern our actions? Astrocyte involvement in rodent behavior. Trends in Neurosciences, 38(9), 535–549. https://doi.org/10.1016/j.tins.2015.07.006
Parada, F. J., & Rossi, A. (2018). If neuroscience needs behavior, what does psychology need? Frontiers in Psychology, 9, 433. https://doi.org/10.3389/fpsyg.2018.00433
Pawluski, J. L., Lonstein, J. S., & Fleming, A. S. (2017). The neurobiology of postpartum anxiety and depression. Trends in Neurosciences, 40(2), 106–120. https://doi.org/10.1016/j.tins.2016.11.009
Pellman, B. A., & Kim, J. J. (2016). What can ethobehavioral studies tell us about the brain’s fear system? Trends in Neurosciences, 39(6), 420–431. https://doi.org/10.1016/j.tins.2016.04.001
Rakic, P. (2009). Evolution of the neocortex: A perspective from developmental biology. Nature Reviews. Neuroscience, 10(10), 724–735. https://doi.org/10.1038/nrn2719
Sarkar, A., Lehto, S. M., Harty, S., Dinan, T. G., Cryan, J. F., & Burnet, P. W. J. (2016). Psychobiotics and the manipulation of Bacteria–Gut–Brain signals. Trends in Neurosciences, 39(11), 763–781. https://doi.org/10.1016/j.tins.2016.09.002
Shenoy, K. V., Sahani, M., & Churchland, M. M. (2013). Cortical control of arm movements: A dynamical systems perspective. Annual Review of Neuroscience, 36, 337–359. https://doi.org/10.1146/annurev-neuro-062111-150509
Siddiqi, S. H., Kording, K. P., Parvizi, J., & Fox, M. D. (2022). Causal mapping of human brain function. Nature Reviews. Neuroscience, 23(6), 361–375. https://doi.org/10.1038/s41583-022-00583-8
Squire, L. R., & Wixted, J. T. (2011). The cognitive neuroscience of human memory since H.M. Annual Review of Neuroscience, 34, 259–288. https://doi.org/10.1146/annurev-neuro-061010-113720
Tallon-Baudry, C. (2023). Interoception: Probing internal state is inherent to perception and cognition. Neuron, 111(12), 1854–1857. https://doi.org/10.1016/j.neuron.2023.04.019
Volk, L., Chiu, S.-L., Sharma, K., & Huganir, R. L. (2015). Glutamate synapses in human cognitive disorders. Annual Review of Neuroscience, 38, 127–149. https://doi.org/10.1146/annurev-neuro-071714-033821
Watabe-Uchida, M., Eshel, N., & Uchida, N. (2017). Neural circuitry of reward prediction error. Annual Review of Neuroscience, 40, 373–394. https://doi.org/10.1146/annurev-neuro-072116-031109
Zeng, H., & Sanes, J. R. (2017). Neuronal cell-type classification: Challenges, opportunities and the path forward. Nature Reviews. Neuroscience. https://doi.org/10.1038/nrn.2017.85